Mitsuru Futakuchi 14th International Biennial Conference on Metastasis Research 2012

Mitsuru Futakuchi

Sadanandam, A., Futakuchi, M., Lyssiotis, C. A., Gibb, W. J., and Singh, R. K. A Cross-Species Analysis of a Mouse Model of Breast Cancer-Specific Osteolysis and Human Bone Metastases using Gene Expression Profiling. BMC Cancer 11, 304. 2011. Nannuru, K. C., Futakuchi, M., Varney, M. L., Vincent, T. M., Marcusson, E. G., and Singh, R. K. Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface. Cancer Res 70, 3494-3504, 2010 3. Futakuchi, M., Nannuru, K. C., Varney, M. L., Sadanandam, A., Nakao, K., Asai, K., Shirai, T., Sato, S. Y., and Singh, R. K. Transforming growth factor-beta signaling at the tumor-bone interface promotes mammary tumor growth and osteoclast activation. Cancer Sci 100, 71-81, 2009 Wilson, T. J., Nannuru, K. C., Futakuchi, M., Sadanandam, A., and Singh, R. K. Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand. Cancer Res 68, 5803-5811, 2008 Lynch CC, Hikosaka A, Acuff HB, Martin MD, Kawai N, Singh RK, Vargo-Gogola TC, Begtrup JL, Peterson TE, Fingleton B, Shirai T, Matrisian LM, Futakuchi M: MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL, Cancer Cell 2005, 7:485-496

Abstracts this author is presenting: