Dr. Masahiro Inoue is the head of Dept. Biochemistry at Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan. Dr. Inoue obtained his M.D. and Ph.D. from Osaka University Medical School and became a postdoctoral fellow with Dr. Doug Hanahan at the University of California, San Francisco, where he revealed the importance of the VEGF gene in tumorigenesis with a transgenic mouse model. Dr. Inoue joined the current Institute in the spring of 2001. He was promoted to Professor of Clinical and Experimental Pathophysiology, Osaka University Graduate School of
Pharmaceutical Sciences in 2011. Dr. Inoue’s recent research focuses on the primary culture of cancer cells. He recently developed a novel method to prepare and culture cancer cells from patients’ tumor samples. The method, CTOS (cancer tissue-originated spheroids), enables easy preparation of pure cancer cells from the biopsy samples with high efficiency. Cancer cells in CTOS preserve original characters including differentiation and polarity even after long term culture. CTOS can generate tumors with metastasis in mice. CTOS can be applicable to personalized medicine as well as the study of cancer biology.
Abstracts this author is presenting: