Erica K Sloan 14th International Biennial Conference on Metastasis Research 2012

Erica K Sloan

Erica Sloan’s research program investigates neural regulation of the tumour microenvironment and its impact on metastasis. Her research aims to understand the cellular and molecular mechanisms of neural-tumour dynamics, with the overarching goal to identify novel targets for pharmacological intervention of cancer metastasis and biomarkers of early cancer progression. Her research demonstrated that sympathetic nervous system activity enhances metastasis from mammary tumours to distant target tissues. Neural regulation of metastasis occurred through beta-adrenergic signalling pathways and was dependent on recruitment of macrophages to the primary mammary tumour. To investigate the impact of pharmacological interventions targeted against neural-tumour interactions - including immunotherapy, small molecular inhibitors and adrenergic antagonists – her lab use advanced optical imaging technology and microscopy for real-time analyses of tumour responses in preclinical trials. Erica Sloan is a research scientist at Monash Institute of Pharmaceutical Sciences, Australia. She is a Senior Lecturer at the Faculty of Pharmacy and Pharmaceutical Sciences at Monash University and holds an adjunct position at University of California, Los Angeles.

Abstracts this author is presenting: