Poster Presentation 14th International Biennial Conference on Metastasis Research 2012

A novel role for the E3 -ligase E6AP in the control of cell invasion and migration (#113)

Mariam Mansour 1 , Ai-leen Chan 1 , Sue Haupt 1 , Cameron Johnstone 1 , Mark Bishton 1 , Nathan Godde 1 , Kamil Wolyniec 1 , Patrick Humbert 1 , Ora Bernard 2 , Ygal Haupt 1
  1. PeterMac Callum Cancer center, Australia, VIC, Australia
  2. St. Vincent's Institute of Medical Research, Melbourne, Victoria 3065, Australia
Publish consent withheld
  1. 1-UBE3A/E6-AP mutations cause Angelman syndrome.Kishino T, Lalande M, Wagstaff J.; Nat Genet 1997 Apr;15(4).
  2. 2- E6AP promotes the degradation of the PML tumor suppressor . Louria-Hayon I, Alsheich-Bartok O, Levav-Cohen Y, Silberman I, Berger M, Grossman T, Matentzoglu K, Jiang YH, Muller S, Scheffner M, Haupt S, Haupt Y. Cell Death Differ. 2009 Aug;16(8):1156-66
  3. 3-E6AP is required for replicative and oncogene-induced senescence in mouse embryo fibroblasts. Levav-Cohen Y, Wolyniec K, Alsheich-Bartok O, Chan AL, Woods SJ, Jiang YH, Haupt S, Haupt Y; Oncogene. 2011 Sep 19.