A novel role for the E3 -ligase E6AP in the control of cell invasion and migration (#113)
Mariam Mansour
1
,
Ai-leen Chan
1
,
Sue Haupt
1
,
Cameron Johnstone
1
,
Mark Bishton
1
,
Nathan Godde
1
,
Kamil Wolyniec
1
,
Patrick Humbert
1
,
Ora Bernard
2
,
Ygal Haupt
1
- PeterMac Callum Cancer center, Australia, VIC, Australia
- St. Vincent's Institute of Medical Research, Melbourne, Victoria 3065, Australia
Publish consent withheld
- 1-UBE3A/E6-AP mutations cause Angelman syndrome.Kishino T, Lalande M, Wagstaff J.; Nat Genet 1997 Apr;15(4).
- 2- E6AP promotes the degradation of the PML tumor suppressor . Louria-Hayon I, Alsheich-Bartok O, Levav-Cohen Y, Silberman I, Berger M, Grossman T, Matentzoglu K, Jiang YH, Muller S, Scheffner M, Haupt S, Haupt Y. Cell Death Differ. 2009 Aug;16(8):1156-66
- 3-E6AP is required for replicative and oncogene-induced senescence in mouse embryo fibroblasts. Levav-Cohen Y, Wolyniec K, Alsheich-Bartok O, Chan AL, Woods SJ, Jiang YH, Haupt S, Haupt Y; Oncogene. 2011 Sep 19.